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Pancreatic cancer cells require an EGF receptor-mediated autocrine pathway for proliferation in serum-free conditions

In-vitro and in-vivo studies have shown that autocrine growth factors and receptors are frequently expressed in human malignancies. Few of these studies, however, provide evidence that the identified autocrine pathway is functional. In this study, a functional autocrine growth pathway in pancreatic...

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Detalles Bibliográficos
Autores principales: Murphy, L O, Cluck, M W, Lovas, S, Ötvös, F, Murphy, R F, Schally, A V, Permert, J, Larsson, J, Knezetic, J A, Adrian, T E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363846/
https://www.ncbi.nlm.nih.gov/pubmed/11286473
http://dx.doi.org/10.1054/bjoc.2001.1698