Cargando…
Pancreatic cancer cells require an EGF receptor-mediated autocrine pathway for proliferation in serum-free conditions
In-vitro and in-vivo studies have shown that autocrine growth factors and receptors are frequently expressed in human malignancies. Few of these studies, however, provide evidence that the identified autocrine pathway is functional. In this study, a functional autocrine growth pathway in pancreatic...
Autores principales: | Murphy, L O, Cluck, M W, Lovas, S, Ötvös, F, Murphy, R F, Schally, A V, Permert, J, Larsson, J, Knezetic, J A, Adrian, T E |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363846/ https://www.ncbi.nlm.nih.gov/pubmed/11286473 http://dx.doi.org/10.1054/bjoc.2001.1698 |
Ejemplares similares
-
Amphiregulin acts as an autocrine growth factor in two human polarizing colon cancer lines that exhibit domain selective EGF receptor mitogenesis
por: Damstrup, L, et al.
Publicado: (1999) -
HB-EGF Signaling Is Required for Glucose-Induced Pancreatic β-Cell Proliferation in Rats
por: Maachi, Hasna, et al.
Publicado: (2020) -
Complex post-transcriptional regulation of EGF-receptor expression by EGF and TGF-α in human prostate cancer cells
por: Seth, D, et al.
Publicado: (1999) -
The relationship between diabetes and pancreatic cancer
por: Wang, Feng, et al.
Publicado: (2003) -
The Transcription Factor AP-1 Is Required for EGF-induced Activation of Rho-like GTPases, Cytoskeletal Rearrangements, Motility, and In Vitro Invasion of A431 Cells
por: Malliri, Angeliki, et al.
Publicado: (1998)