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Generation of cytotoxic T cell responses to an HLA-A24 restricted epitope peptide derived from wild-type p53
Mutations in the p53 gene are the most common genetic alterations found in human tumours, and these mutations result in high levels of p53 protein in the tumour cells. Since the expression levels of wild-type p53 in nonmalignant tissue are usually much lower in contrast, the p53 protein is an attrac...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363851/ https://www.ncbi.nlm.nih.gov/pubmed/11308253 http://dx.doi.org/10.1054/bjoc.2000.1715 |