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Induction of apoptosis in prostate carcinoma cells by BH3 peptides which inhibit Bak/Bcl-2 interactions

Interactions between proteins of the Bcl-2 family play an important role in the regulation of apoptosis. Anti-apoptotic family members can heterodimerize with pro-apoptotic family members and antagonize their function, thus protecting against death. In cells protected from death by overexpression of...

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Detalles Bibliográficos
Autores principales: Finnegan, N M, Curtin, J F, Prevost, G, Morgan, B, Cotter, T G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363905/
https://www.ncbi.nlm.nih.gov/pubmed/11437412
http://dx.doi.org/10.1054/bjoc.2001.1850