Cargando…
Induction of apoptosis in prostate carcinoma cells by BH3 peptides which inhibit Bak/Bcl-2 interactions
Interactions between proteins of the Bcl-2 family play an important role in the regulation of apoptosis. Anti-apoptotic family members can heterodimerize with pro-apoptotic family members and antagonize their function, thus protecting against death. In cells protected from death by overexpression of...
Autores principales: | Finnegan, N M, Curtin, J F, Prevost, G, Morgan, B, Cotter, T G |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363905/ https://www.ncbi.nlm.nih.gov/pubmed/11437412 http://dx.doi.org/10.1054/bjoc.2001.1850 |
Ejemplares similares
-
Characterization of an alternative BAK-binding site for BH3 peptides
por: Ye, Kaiqin, et al.
Publicado: (2020) -
Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization
por: Dai, Haiming, et al.
Publicado: (2011) -
Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak
por: Uren, Rachel T., et al.
Publicado: (2007) -
BH3 Peptides Induce Mitochondrial Fission and Cell Death Independent of BAX/BAK
por: Shroff, Emelyn H., et al.
Publicado: (2009) -
Cell-Permeable Bak BH3 Peptide Induces Chemosensitization of Hematologic Malignant Cells
por: Ugarte-Alvarez, Omar, et al.
Publicado: (2020)