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Induction of matrix metalloproteinase-1 (MMP-1) during epidermal invasion of the stroma in human skin organ culture: keratinocyte stimulation of fibroblast MMP-1 production

Organ cultures of human skin were incubated for 8 days under growth factor-free conditions or exposed to 10 ng ml(−1) of human recombinant epidermal growth factor (EGF) during the incubation period. Normal histological features were preserved in the absence of growth factor, while epithelial cells u...

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Detalles Bibliográficos
Autores principales: Moon, S E, Dame, M K, Remick, D R, Elder, J T, Varani, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363942/
https://www.ncbi.nlm.nih.gov/pubmed/11720451
http://dx.doi.org/10.1054/bjoc.2001.2122