Internalisation enhances photo-induced cytotoxicity of monoclonal antibody-phthalocyanine conjugates

Immunophototherapy of cancer combines the specificity of a monoclonal antibody (MAb) to an overexpressed tumor marker with the phototoxic properties of the conjugated dye. To analyze the potential role of internalisation of the dye on photo-induced cytotoxicity, we compared two target antigens, carc...

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Detalles Bibliográficos
Autores principales: Carcenac, M, Dorvillius, M, Garambois, V, Glaussel, F, Larroque, Ch, Langlois, R, Hynes, N E, van Lier, J E, Pèlegrin, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363963/
https://www.ncbi.nlm.nih.gov/pubmed/11742503
http://dx.doi.org/10.1054/bjoc.2001.2170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363963/
https://www.ncbi.nlm.nih.gov/pubmed/11742503
http://dx.doi.org/10.1054/bjoc.2001.2170

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