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gp100/pmel17 and tyrosinase encode multiple epitopes recognized by Th1-type CD4+T cells

CD4+ T cells modulate the magnitude and durability of CTL responses in vivo, and may serve as effector cells in the tumour microenvironment. In order to identify the tumour epitopes recognized by tumour-reactive human CD4+ T cells, we combined the use of an HLA-DR4/peptide binding algorithm with an...

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Detalles Bibliográficos
Autores principales: Kierstead, L S, Ranieri, E, Olson, W, Brusic, V, Sidney, J, Sette, A, Kasamon, Y L, Slingluff, C L, Kirkwood, J M, Storkus, W J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363969/
https://www.ncbi.nlm.nih.gov/pubmed/11742496
http://dx.doi.org/10.1054/bjoc.2001.2160