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Association of c-Raf expression with survival and its targeting with antisense oligonucleotides in ovarian cancer
c-Raf is an essential component of the extracellular related kinase (ERK) signal transduction pathway. Immunohistochemical staining indicated that c-Raf was present in 49/53 ovarian adenocarcinomas investigated and high c-Raf expression correlated significantly with poor survival (P = 0.002). c-Raf...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363986/ https://www.ncbi.nlm.nih.gov/pubmed/11742498 http://dx.doi.org/10.1054/bjoc.2001.2139 |