Association of c-Raf expression with survival and its targeting with antisense oligonucleotides in ovarian cancer

c-Raf is an essential component of the extracellular related kinase (ERK) signal transduction pathway. Immunohistochemical staining indicated that c-Raf was present in 49/53 ovarian adenocarcinomas investigated and high c-Raf expression correlated significantly with poor survival (P = 0.002). c-Raf...

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Detalles Bibliográficos
Autores principales: McPhillips, F, Mullen, P, Monia, B P, Ritchie, A A, Dorr, F A, Smyth, J F, Langdon, S P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363986/
https://www.ncbi.nlm.nih.gov/pubmed/11742498
http://dx.doi.org/10.1054/bjoc.2001.2139

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