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Increased endothelin-1 in colorectal cancer and reduction of tumour growth by ET (A) receptor antagonism
Endothelin-1 (ET-1) is a vasoconstrictor peptide which stimulates proliferation in vitro in different cell types, including colorectal cancer cells. Raised ET-1 levels have been detected both on tissue specimens and in the plasma of patients with cancers. To investigate the role of ET-1 in colorecta...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363991/ https://www.ncbi.nlm.nih.gov/pubmed/11742499 http://dx.doi.org/10.1054/bjoc.2001.2193 |