Cargando…

Increased endothelin-1 in colorectal cancer and reduction of tumour growth by ET (A) receptor antagonism

Endothelin-1 (ET-1) is a vasoconstrictor peptide which stimulates proliferation in vitro in different cell types, including colorectal cancer cells. Raised ET-1 levels have been detected both on tissue specimens and in the plasma of patients with cancers. To investigate the role of ET-1 in colorecta...

Descripción completa

Detalles Bibliográficos
Autores principales: Asham, E, Shankar, A, Loizidou, M, Fredericks, S, Miller, K, Boulos, P B, Burnstock, G, Taylor, I
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363991/
https://www.ncbi.nlm.nih.gov/pubmed/11742499
http://dx.doi.org/10.1054/bjoc.2001.2193