Uptake of IgG in osteosarcoma correlates inversely with interstitial fluid pressure, but not with interstitial constituents

The uptake of therapeutic macromolecules in solid tumours is assumed to be hindered by the heterogeneous vascular network, the high interstitial fluid pressure, and the extracellular matrix. To study the impact of these factors, we measured the uptake of fluorochrome-labelled IgG using confocal lase...

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Detalles Bibliográficos
Autores principales: Davies, C de Lange, Engesæter, B Ø, Haug, I, Ormberg, I W, Halgunset, J, Brekken, C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363997/
https://www.ncbi.nlm.nih.gov/pubmed/11747342
http://dx.doi.org/10.1054/bjoc.2001.2180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363997/
https://www.ncbi.nlm.nih.gov/pubmed/11747342
http://dx.doi.org/10.1054/bjoc.2001.2180

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