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Uptake of IgG in osteosarcoma correlates inversely with interstitial fluid pressure, but not with interstitial constituents
The uptake of therapeutic macromolecules in solid tumours is assumed to be hindered by the heterogeneous vascular network, the high interstitial fluid pressure, and the extracellular matrix. To study the impact of these factors, we measured the uptake of fluorochrome-labelled IgG using confocal lase...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363997/ https://www.ncbi.nlm.nih.gov/pubmed/11747342 http://dx.doi.org/10.1054/bjoc.2001.2180 |