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Expression of the hypermethylated in cancer gene (HIC-1) is associated with good outcome in human breast cancer

A new cancer gene, HIC-1 (Hypermethylated in Cancer) telomeric to p53 on chromosome 17p may be of clinical importance in sporadic breast cancer. Regional DNA hypermethylation of 17p13.3 resulting in suppression of gene expression has been shown to precede 17p structural changes in human carcinogenes...

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Detalles Bibliográficos
Autores principales: Nicoll, G, Crichton, D N, McDowell, H E, Kernohan, N, Hupp, T R, Thompson, A M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363999/
https://www.ncbi.nlm.nih.gov/pubmed/11747329
http://dx.doi.org/10.1054/bjoc.2001.2163