Mutation analysis of the CHK2 gene in families with hereditary breast cancer

Recently CHK2 was functionally linked to the p53 pathway, and mutations in these two genes seem to result in a similar Li–Fraumeni syndrome (LFS) or Li–Fraumeni-like syndrome (LFL) multi-cancer phenotype frequently including breast cancer. As CHK2 has been found to bind and regulate BRCA1, the produ...

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Detalles Bibliográficos
Autores principales: Allinen, M, Huusko, P, Mäntyniemi, S, Launonen, V, Winqvist, R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364033/
https://www.ncbi.nlm.nih.gov/pubmed/11461078
http://dx.doi.org/10.1054/bjoc.2001.1858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364033/
https://www.ncbi.nlm.nih.gov/pubmed/11461078
http://dx.doi.org/10.1054/bjoc.2001.1858

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