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The distribution and expression of the Bloom's syndrome gene product in normal and neoplastic human cells
Bloom's syndrome (BS) is an autosomal recessive disorder associated with a predisposition to cancers of all types. Cells from BS sufferers display extreme genomic instability. The BS gene product, BLM, is a 159 kDa DNA helicase enzyme belonging to the RecQ family. Here, we have analysed the dis...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364038/ https://www.ncbi.nlm.nih.gov/pubmed/11461087 http://dx.doi.org/10.1054/bjoc.2001.1874 |