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Genetic heterogeneity and clonal evolution in neuroblastoma

Tumour heterogeneity and clonal evolution at the genetic level may explain the development of malignant or resistant disease during clinical progression of neuroblastoma (NB). In this report we use 1p allelic analysis and DNA ploidy to evaluate clonal heterogeneity and clonal selection in vivo. We s...

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Detalles Bibliográficos
Autores principales: Mora, J, Cheung, N-K V, Gerald, W L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364052/
https://www.ncbi.nlm.nih.gov/pubmed/11461074
http://dx.doi.org/10.1054/bjoc.2001.1849