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Antagonists of retinoic acid receptors (RARs) are potent growth inhibitors of prostate carcinoma cells

Novel synthetic antagonists of retinoic acid receptors (RARs) have been developed. To avoid interference by serum retinoids when testing these compounds, we established serum-free grown sub-lines (>3 years) of the prostate carcinoma lines LNCaP, PC3 and DU145. A high affinity pan-RAR antagonist (...

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Detalles Bibliográficos
Autores principales: Hammond, L A, Krinks, C H Van, Durham, J, Tomkins, S E, Burnett, R D, Jones, E L, Chandraratna, R A S, Brown, G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364081/
https://www.ncbi.nlm.nih.gov/pubmed/11487280
http://dx.doi.org/10.1054/bjoc.2001.1939