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A common founder for the V126D CDKN2A mutation in seven North American melanoma-prone families

One of the most common melanoma-related CDKN2A mutations reported in North America is the V126D mutation. We examined nine markers surrounding CDKN2A in three American and four Canadian families carrying the V126D mutation. All seven families had a haplotype consistent with a common ancestor/founder...

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Detalles Bibliográficos
Autores principales: Goldstein, A M, Liu, L, Shennan, M G, Hogg, D, Tucker, M A, Struewing, J P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364106/
https://www.ncbi.nlm.nih.gov/pubmed/11506491
http://dx.doi.org/10.1054/bjoc.2001.1944