Genetic analysis of the APC gene regions involved in attenuated APC phenotype in Israeli patients with early onset and familial colorectal cancer

The genetic basis for the majority of early onset or non-syndromic ‘familial’ colorectal cancer (CRC) is unknown. Attenuated APC phenotype is characterized by relatively few colonic polyps, early age at onset of colon cancer compared with the general population, and inactivating germline mutations w...

Descripción completa

Detalles Bibliográficos
Autores principales: Figer, A, Irmin, L, Geva, R, Flex, D, Sulkes, A, Friedman, E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364108/
https://www.ncbi.nlm.nih.gov/pubmed/11506490
http://dx.doi.org/10.1054/bjoc.2001.1959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364108/
https://www.ncbi.nlm.nih.gov/pubmed/11506490
http://dx.doi.org/10.1054/bjoc.2001.1959

Ejemplares similares