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Initiation of human colon cancer cell proliferation by trypsin acting at protease-activated receptor-2

The protease-activated receptor-2 (PAR-2) is a G protein-coupled receptor that is cleaved and activated by trypsin. We investigated the expression of PAR-2 and the role of trypsin in cell proliferation in human colon cancer cell lines. A total of 10 cell lines were tested for expression of PAR-2 mRN...

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Detalles Bibliográficos
Autores principales: Darmoul, D, Marie, J-C, Devaud, H, Gratio, V, Laburthe, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364111/
https://www.ncbi.nlm.nih.gov/pubmed/11531266
http://dx.doi.org/10.1054/bjoc.2001.1976