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Initiation of human colon cancer cell proliferation by trypsin acting at protease-activated receptor-2
The protease-activated receptor-2 (PAR-2) is a G protein-coupled receptor that is cleaved and activated by trypsin. We investigated the expression of PAR-2 and the role of trypsin in cell proliferation in human colon cancer cell lines. A total of 10 cell lines were tested for expression of PAR-2 mRN...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364111/ https://www.ncbi.nlm.nih.gov/pubmed/11531266 http://dx.doi.org/10.1054/bjoc.2001.1976 |