Enhanced etoposide sensitivity following adenovirus-mediated human topoisomerase II α gene transfer is independent of topoisomerase II β

The roles that the α and β isoforms of topoisomerase II (topo II) play in anticancer drug action were determined using MDA-VP etoposide-resistant human breast cancer cells and a newly constructed adenoviral vector containing the topo IIα gene (Ad-topo IIα). MDA-VP cells were more resistant to etopos...

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Detalles Bibliográficos
Autores principales: Zhou, Z, Zwelling, L A, Ganapathi, R, Kleinerman, E S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364113/
https://www.ncbi.nlm.nih.gov/pubmed/11531262
http://dx.doi.org/10.1054/bjoc.2001.1966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364113/
https://www.ncbi.nlm.nih.gov/pubmed/11531262
http://dx.doi.org/10.1054/bjoc.2001.1966

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