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TP53 mutations, amplification of P63 and expression of cell cycle proteins in squamous cell carcinoma of the oesophagus from a low incidence area in Western Europe

In Europe, high incidence rates of oesophageal squamous cell carcinoma (SCCE) are observed in western France (Normandy and Brittany) and in north-eastern Italy. Analysis of TP53 mutations in tumours from these regions has shown a high prevalence of mutations at A:T basepairs that may result from DNA...

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Detalles Bibliográficos
Autores principales: Tanière, P, Martel-Planche, G, Saurin, J C, Lombard-Bohas, C, Berger, F, Scoazec, J Y, Hainaut, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364124/
https://www.ncbi.nlm.nih.gov/pubmed/11531258
http://dx.doi.org/10.1054/bjoc.2001.1990