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A Bayesian re-assessment of two Phase II trials of gemcitabine in metastatic nasopharyngeal cancer
The Simon two-stage minimax design is a popular statistical design used in Phase II clinical trials. The analysis of the data arising from the design typically involves the use of frequentist statistics. This paper presents an alternative, Bayesian, approach to the design and analysis of Phase II cl...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364147/ https://www.ncbi.nlm.nih.gov/pubmed/11953813 http://dx.doi.org/10.1038/sj.bjc.6600199 |