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A Bayesian re-assessment of two Phase II trials of gemcitabine in metastatic nasopharyngeal cancer

The Simon two-stage minimax design is a popular statistical design used in Phase II clinical trials. The analysis of the data arising from the design typically involves the use of frequentist statistics. This paper presents an alternative, Bayesian, approach to the design and analysis of Phase II cl...

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Detalles Bibliográficos
Autores principales: Tan, S-B, Machin, D, Tai, B-C, Foo, K-F, Tan, E-H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364147/
https://www.ncbi.nlm.nih.gov/pubmed/11953813
http://dx.doi.org/10.1038/sj.bjc.6600199