Dominant negative knockout of p53 abolishes ErbB2-dependent apoptosis and permits growth acceleration in human breast cancer cells

We previously reported that the ErbB2 oncoprotein prolongs and amplifies growth factor signalling by impairing ligand-dependent downregulation of hetero-oligomerised epidermal growth factor receptors. Here we show that treatment of A431 cells with different epidermal growth factor receptor ligands c...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, G C, Hobbs, S, Walton, M, Epstein, R J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Molecular and Cellular Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364174/
https://www.ncbi.nlm.nih.gov/pubmed/11953857
http://dx.doi.org/10.1038/sj.bjc.6600219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364174/
https://www.ncbi.nlm.nih.gov/pubmed/11953857
http://dx.doi.org/10.1038/sj.bjc.6600219

Ejemplares similares