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Dominant negative knockout of p53 abolishes ErbB2-dependent apoptosis and permits growth acceleration in human breast cancer cells

We previously reported that the ErbB2 oncoprotein prolongs and amplifies growth factor signalling by impairing ligand-dependent downregulation of hetero-oligomerised epidermal growth factor receptors. Here we show that treatment of A431 cells with different epidermal growth factor receptor ligands c...

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Detalles Bibliográficos
Autores principales:	Huang, G C, Hobbs, S, Walton, M, Epstein, R J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2002
Materias:	Molecular and Cellular Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364174/ https://www.ncbi.nlm.nih.gov/pubmed/11953857 http://dx.doi.org/10.1038/sj.bjc.6600219

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