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Laminin γ1 chain peptide, C-16 (KAFDITYVRLKF), promotes migration, MMP-9 secretion, and pulmonary metastasis of B16–F10 mouse melanoma cells

Laminin-1, a heterotrimer of α1, β1, and γ1 chains specific to basement membrane, promotes cell adhesion and migration, proteinase secretion and metastases of tumour cells. Several active sites on the α1 chain have been found to promote B16–F10 melanoma lung colonisation and here we have determined...

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Detalles Bibliográficos
Autores principales: Kuratomi, Y, Nomizu, M, Tanaka, K, Ponce, M L, Komiyama, S, Kleinman, H K, Yamada, Y
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364181/
https://www.ncbi.nlm.nih.gov/pubmed/11953867
http://dx.doi.org/10.1038/sj.bjc.6600187