Phosphorothioate oligonucleotides, suramin and heparin inhibit DNA-dependent protein kinase activity

Phosphorothioate oligonucleotides and suramin bind to heparin binding proteins including DNA polymerases, and inhibit their functions. In the present study, we report inhibition of DNA-dependent protein kinase activity by phosphorothioate oligonucleotides, suramin and heparin. Inhibitory effect of p...

Descripción completa

Detalles Bibliográficos
Autores principales: Hosoi, Y, Matsumoto, Y, Tomita, M, Enomoto, A, Morita, A, Sakai, K, Umeda, N, Zhao, H-J, Nakagawa, K, Ono, T, Suzuki, N
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364188/
https://www.ncbi.nlm.nih.gov/pubmed/11953863
http://dx.doi.org/10.1038/sj.bjc.6600191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364188/
https://www.ncbi.nlm.nih.gov/pubmed/11953863
http://dx.doi.org/10.1038/sj.bjc.6600191

Ejemplares similares