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Phosphorothioate oligonucleotides, suramin and heparin inhibit DNA-dependent protein kinase activity

Phosphorothioate oligonucleotides and suramin bind to heparin binding proteins including DNA polymerases, and inhibit their functions. In the present study, we report inhibition of DNA-dependent protein kinase activity by phosphorothioate oligonucleotides, suramin and heparin. Inhibitory effect of p...

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Detalles Bibliográficos
Autores principales:	Hosoi, Y, Matsumoto, Y, Tomita, M, Enomoto, A, Morita, A, Sakai, K, Umeda, N, Zhao, H-J, Nakagawa, K, Ono, T, Suzuki, N
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2002
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364188/ https://www.ncbi.nlm.nih.gov/pubmed/11953863 http://dx.doi.org/10.1038/sj.bjc.6600191

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