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Cancer Research UK procedures in manufacture and toxicology of radiotracers intended for Pre-phase I positron emission tomography studies in cancer patients

Radiolabelled compounds formulated for injection (radiopharmaceuticals), are increasingly being employed in drug development studies. These can be used in tracer amounts for either pharmacokinetic or pharmacodynamic studies. Such radiotracer studies can also be carried out early in man, even prior t...

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Detalles Bibliográficos
Autores principales: Aboagye, E O, Luthra, S K, Brady, F, Poole, K, Anderson, H, Jones, T, Boobis, A, Burtles, S S, Price, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364192/
https://www.ncbi.nlm.nih.gov/pubmed/11953847
http://dx.doi.org/10.1038/sj.bjc.6600212