Cargando…
Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response
Inflammatory disease states (infection, arthritis) are associated with reduced drug oxidation by the cytochrome P450 3A system. Many chemotherapy agents are metabolised through this pathway, and disease may therefore influence inter-individual differences in drug pharmacokinetics. The purpose of thi...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2002
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364233/ https://www.ncbi.nlm.nih.gov/pubmed/12177794 http://dx.doi.org/10.1038/sj.bjc.6600448 |