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DNA topoisomerase I and II expression in drug resistantgerm cell tumours

A small number of testicular germ cell tumours are refractory to current chemotherapy regimens. DNA topoisomerase I is the target for several new drugs and a potential candidate treatment for chemorefractory germ cell tumours. DNA topoisomerase IIα is the target for etoposide, which is currently use...

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Detalles Bibliográficos
Autores principales: Berney, D M, Shamash, J, Gaffney, J, Jordan, S, Oliver, R T D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364243/
https://www.ncbi.nlm.nih.gov/pubmed/12237772
http://dx.doi.org/10.1038/sj.bjc.6600472