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DNA topoisomerase I and II expression in drug resistantgerm cell tumours

A small number of testicular germ cell tumours are refractory to current chemotherapy regimens. DNA topoisomerase I is the target for several new drugs and a potential candidate treatment for chemorefractory germ cell tumours. DNA topoisomerase IIα is the target for etoposide, which is currently use...

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Detalles Bibliográficos
Autores principales:	Berney, D M, Shamash, J, Gaffney, J, Jordan, S, Oliver, R T D
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2002
Materias:	Molecular and Cellular Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364243/ https://www.ncbi.nlm.nih.gov/pubmed/12237772 http://dx.doi.org/10.1038/sj.bjc.6600472

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