Cytotoxic targeting of F9 teratocarcinoma tumours with anti-ED-B fibronectin scFv antibody modified liposomes

We prepared small unilamellar liposomes derivatised with single chain antibody fragments specific for the ED-B domain of B-fibronectin. This extracellular matrix associated protein is expressed around newly forming blood vessels in the vicinity of many types of tumours. The single chain antibody fra...

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Detalles Bibliográficos
Autores principales: Marty, C, Odermatt, B, Schott, H, Neri, D, Ballmer-Hofer, K, Klemenz, R, Schwendener, R A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364274/
https://www.ncbi.nlm.nih.gov/pubmed/12085265
http://dx.doi.org/10.1038/sj.bjc.6600423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364274/
https://www.ncbi.nlm.nih.gov/pubmed/12085265
http://dx.doi.org/10.1038/sj.bjc.6600423

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