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Cytotoxic targeting of F9 teratocarcinoma tumours with anti-ED-B fibronectin scFv antibody modified liposomes
We prepared small unilamellar liposomes derivatised with single chain antibody fragments specific for the ED-B domain of B-fibronectin. This extracellular matrix associated protein is expressed around newly forming blood vessels in the vicinity of many types of tumours. The single chain antibody fra...
Autores principales: | Marty, C, Odermatt, B, Schott, H, Neri, D, Ballmer-Hofer, K, Klemenz, R, Schwendener, R A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364274/ https://www.ncbi.nlm.nih.gov/pubmed/12085265 http://dx.doi.org/10.1038/sj.bjc.6600423 |
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