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Paradoxical expression of cell cycle inhibitor p27 in endometrioid adenocarcinoma of the uterine corpus – correlation with proliferation and clinicopathological parameters

p27 is regarded as a cyclin-dependent kinase inhibitor of the G1-to-S cell cycle progression by suppressing the kinase activity of cyclin/cyclin-dependent kinase complex. This study aimed to investigate p27 expression in the normal endometrium and endometrioid adenocarcinoma of the uterine corpus an...

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Detalles Bibliográficos
Autores principales: Watanabe, J, Sato, H, Kanai, T, Kamata, Y, Jobo, T, Hata, H, Fujisawa, T, Ohno, E, Kameya, T, Kuramoto, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364278/
https://www.ncbi.nlm.nih.gov/pubmed/12085261
http://dx.doi.org/10.1038/sj.bjc.6600434