Transforming Growth Factor-β2 protects the small intestine during methotrexate treatment in rats possibly by reducing stem cell cycling

During chemo- and radiation therapy, the balance between epithelial cell proliferation, differentiation, and cell death at the villus tip is disrupted by premature death of dividing epithelial cells. This will subsequently lead to the onset of mucosal barrier injury in the whole gastrointestinal tra...

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Detalles Bibliográficos
Autores principales: van't Land, B, Meijer, H P, Frerichs, J, Koetsier, M, Jager, D, Smeets, R L, M'Rabet, L, Hoijer, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364282/
https://www.ncbi.nlm.nih.gov/pubmed/12085266
http://dx.doi.org/10.1038/sj.bjc.6600342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364282/
https://www.ncbi.nlm.nih.gov/pubmed/12085266
http://dx.doi.org/10.1038/sj.bjc.6600342

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