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Reduced risk of synovial sarcoma in females: X-chromosome inactivation?
Synovial sarcoma shows a characteristic t(X;18) translocation but not the expected female predominance in incidence. We speculate that, among females, one X-chromosome is inactivated and that only the translocation to an active X-chromosome leads to development of synovial sarcoma. Population-based...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364289/ https://www.ncbi.nlm.nih.gov/pubmed/12085251 http://dx.doi.org/10.1038/sj.bjc.6600362 |