Teratogenic and Embryocidal Effects of Zidovudine (AZT) in Sprague-Dawley Rats

Objective: The purpose of the present investigation was to analyze the effets of zidovudine on the postimplantation embryo and fetus. Methods: Pregnant Sprague-Dawley rats were given various doses (10 mg/kg, 30 mg/kg, 150 mg/kg) of zidovudine or saline by an endotracheal tube during the period of em...

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Detalles Bibliográficos
Autores principales: Christmas, James T., Little, Bertis B., Knoll, Kraig A., Bawdon, Roger E., Gilstrap III, Larry C.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364389/
https://www.ncbi.nlm.nih.gov/pubmed/18475397
http://dx.doi.org/10.1155/S1064744995000068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364389/
https://www.ncbi.nlm.nih.gov/pubmed/18475397
http://dx.doi.org/10.1155/S1064744995000068

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