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Teratogenic and Embryocidal Effects of Zidovudine (AZT) in Sprague-Dawley Rats

Objective: The purpose of the present investigation was to analyze the effets of zidovudine on the postimplantation embryo and fetus. Methods: Pregnant Sprague-Dawley rats were given various doses (10 mg/kg, 30 mg/kg, 150 mg/kg) of zidovudine or saline by an endotracheal tube during the period of em...

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Detalles Bibliográficos
Autores principales:	Christmas, James T., Little, Bertis B., Knoll, Kraig A., Bawdon, Roger E., Gilstrap III, Larry C.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1995
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364389/ https://www.ncbi.nlm.nih.gov/pubmed/18475397 http://dx.doi.org/10.1155/S1064744995000068

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