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Parasite Burden and CD36-Mediated Sequestration Are Determinants of Acute Lung Injury in an Experimental Malaria Model

Although acute lung injury (ALI) is a common complication of severe malaria, little is known about the underlying molecular basis of lung dysfunction. Animal models have provided powerful insights into the pathogenesis of severe malaria syndromes such as cerebral malaria (CM); however, no model of m...

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Detalles Bibliográficos
Autores principales: Lovegrove, Fiona E., Gharib, Sina A., Peña-Castillo, Lourdes, Patel, Samir N., Ruzinski, John T., Hughes, Timothy R., Liles, W. Conrad, Kain, Kevin C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364663/
https://www.ncbi.nlm.nih.gov/pubmed/18483551
http://dx.doi.org/10.1371/journal.ppat.1000068