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Kindlin-2 (Mig-2): a co-activator of β(3) integrins

Integrin activation is essential for dynamically linking the extracellular environment and cytoskeletal/signaling networks. Activation is controlled by integrins' short cytoplasmic tails (CTs). It is widely accepted that the head domain of talin (talin-H) can mediate integrin activation by bind...

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Detalles Bibliográficos
Autores principales: Ma, Yan-Qing, Qin, Jun, Wu, Chuanyue, Plow, Edward F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364684/
https://www.ncbi.nlm.nih.gov/pubmed/18458155
http://dx.doi.org/10.1083/jcb.200710196