FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

Autophagy is a membrane-mediated intracellular degradation system. The serine/threonine kinase Atg1 plays an essential role in autophagosome formation. However, the role of the mammalian Atg1 homologues UNC-51–like kinase (ULK) 1 and 2 are not yet well understood. We found that murine ULK1 and 2 loc...

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Detalles Bibliográficos
Autores principales: Hara, Taichi, Takamura, Akito, Kishi, Chieko, Iemura, Shun-ichiro, Natsume, Tohru, Guan, Jun-Lin, Mizushima, Noboru
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364687/
https://www.ncbi.nlm.nih.gov/pubmed/18443221
http://dx.doi.org/10.1083/jcb.200712064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364687/
https://www.ncbi.nlm.nih.gov/pubmed/18443221
http://dx.doi.org/10.1083/jcb.200712064

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