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Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K–Akt signaling

Phosphoinositide-3 kinase (PI3K)/Akt signaling is activated by growth factors such as insulin and epidermal growth factor (EGF) and regulates several functions such as cell cycling, apoptosis, cell growth, and cell migration. Here, we find that Kank is an Akt substrate located downstream of PI3K and...

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Detalles Bibliográficos
Autores principales: Kakinuma, Naoto, Roy, Badal Chandra, Zhu, Yun, Wang, Yong, Kiyama, Ryoiti
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364698/
https://www.ncbi.nlm.nih.gov/pubmed/18458160
http://dx.doi.org/10.1083/jcb.200707022