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Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K–Akt signaling
Phosphoinositide-3 kinase (PI3K)/Akt signaling is activated by growth factors such as insulin and epidermal growth factor (EGF) and regulates several functions such as cell cycling, apoptosis, cell growth, and cell migration. Here, we find that Kank is an Akt substrate located downstream of PI3K and...
Autores principales: | Kakinuma, Naoto, Roy, Badal Chandra, Zhu, Yun, Wang, Yong, Kiyama, Ryoiti |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364698/ https://www.ncbi.nlm.nih.gov/pubmed/18458160 http://dx.doi.org/10.1083/jcb.200707022 |
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