Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division

Rac1 regulates a wide variety of cellular processes. The polybasic region of the Rac1 C terminus functions both as a plasma membrane–targeting motif and a nuclear localization sequence (NLS). We show that a triproline N-terminal to the polybasic region contributes to the NLS, which is cryptic in the...

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Detalles Bibliográficos
Autores principales: Michaelson, David, Abidi, Wasif, Guardavaccaro, Daniele, Zhou, Mo, Ahearn, Ian, Pagano, Michele, Philips, Mark R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364699/
https://www.ncbi.nlm.nih.gov/pubmed/18443222
http://dx.doi.org/10.1083/jcb.200801047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364699/
https://www.ncbi.nlm.nih.gov/pubmed/18443222
http://dx.doi.org/10.1083/jcb.200801047

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