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Cdc14B depletion leads to centriole amplification, and its overexpression prevents unscheduled centriole duplication

Centrosome duplication is tightly controlled in coordination with DNA replication. The molecular mechanism of centrosome duplication remains unclear. Previous studies found that a fraction of human proline-directed phosphatase Cdc14B associates with centrosomes. However, Cdc14B's involvement in...

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Detalles Bibliográficos
Autores principales: Wu, Jun, Cho, Hyekyung P., Rhee, David B., Johnson, Dabney K., Dunlap, John, Liu, Yie, Wang, Yisong
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364701/
https://www.ncbi.nlm.nih.gov/pubmed/18458157
http://dx.doi.org/10.1083/jcb.200710127