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Cdc14B depletion leads to centriole amplification, and its overexpression prevents unscheduled centriole duplication
Centrosome duplication is tightly controlled in coordination with DNA replication. The molecular mechanism of centrosome duplication remains unclear. Previous studies found that a fraction of human proline-directed phosphatase Cdc14B associates with centrosomes. However, Cdc14B's involvement in...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364701/ https://www.ncbi.nlm.nih.gov/pubmed/18458157 http://dx.doi.org/10.1083/jcb.200710127 |