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The formin mDia2 stabilizes microtubules independently of its actin nucleation activity

A critical microtubule (MT) polarization event in cell migration is the Rho/mDia-dependent stabilization of a subset of MTs oriented toward the direction of migration. Although mDia nucleates actin filaments, it is unclear whether this or a separate activity of mDia underlies MT stabilization. We ge...

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Detalles Bibliográficos
Autores principales: Bartolini, Francesca, Moseley, James B., Schmoranzer, Jan, Cassimeris, Lynne, Goode, Bruce L., Gundersen, Gregg G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364705/
https://www.ncbi.nlm.nih.gov/pubmed/18458159
http://dx.doi.org/10.1083/jcb.200709029